talks

Download

talks@lists.cs.princeton.edu

February 2014

3 participants
12 discussions

Colloquium Speaker Debora Marks Thurs Feb 6, 4:30pm
by Nicole E. Wagenblast 06 Feb '14

06 Feb '14

Debora Marks , Harvard Medical School Thursday, February 6, 4:30pm Computer Science 105 Abstract: Attributes of living systems are constrained in evolution. An alternative to the analysis of conserved attributes ('characters') is analysis of functional interactions ('couplings') that cause conservation. For proteins, the evolutionary sequence record can be exploited to provide exquisitely accurate information about 3D structures and functional sites. Recent progress is based on high throughput sequencing as an experimental technology and global probability models under the maximum entropy principle as a key theoretical tool. I will describe how these advances are used in accurate prediction of 3D interactions, complexes, protein plasticity, designing proteins for synthetic biology and therapeutics - and extrapolate to the study of the effects of human genetic variation. There is a now major opportunity to link genomic information to phenotype and apply this to concrete engineering and health problems, such as disease likelihood, the emergence of drug resistance. My lab will concentrate on four interrelated areas at different scales of biology that address the challenge to infer causality in biological information. Debora has a PhD in computational biology and a track record of developing novel algorithms and statistics to successfully address unsolved biological problems. She has a passion for statistics and is driven by a desire to understand and interpret human genetic variation.

1 2

4:30pm Wed Mar 12 Cerf & Kahn Public Lecture about the Internet in Friend 101 (arrive early!)
by Jennifer Rexford 04 Feb '14

04 Feb '14

What: Fathers of the Internet reflecting on the evolution of the Internet. (and a celebration of the 40th anniversary of the invention of TCP/IP protocol for the Internet by Cerf & Kahn in 1974.) Who: Vinton Cerf (Chief Internet Evangelist at Google) and Robert Kahn (CEO of Corporation for National Research Initiatives), whose pioneering work on the Internet has been widely recognized by numerous awards, including the US Presidential Medal of Freedom, the US National Medal of Technology, and the ACM Turing Award, will together give a public duet lecture on “Perspectives on the Internet and its Evolution.” When: March 12, 2014. 4:30-5:30pm. Seating starts at 4pm. Where: Princeton University, Friend Center Auditorium 101. Detail: This is an open lecture to general public. No fee or ticket required. Seating available on first-come-first-served basis, and starts at 4pm. Website (including direction): http://edgelab-events.princeton.edu

1 0