- talks - lists.cs.princeton.edu

cookies
by Ginny Hogan 07 Mar '07

07 Mar '07

Cookies are now available in the tea room -

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Speaker Today - Computer Science Rm 105 - 4:15pm
by Ginny Hogan 07 Mar '07

07 Mar '07

Christina Leslie, Columbia University, will present her talk "Learning Predictive Models Of Gene Regulation" at 4:15pm today COS Room 105 - Tea will be at 3:45pm.

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Speaker March 8 -Colloquium Speaker
by Ginny Hogan 06 Mar '07

06 Mar '07

Scott Aaronson, University of Waterloo will present his talk "The Limits of Quantum Computers", Thursday, 3/8 - 4:15pm, Computer Science Room 105.

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/@rts: Wolfgang Staehle, Tuesday, 3/6/07
by Adam Finkelstein 05 Mar '07

05 Mar '07

Talk announcement for SlashArts - tomorrow afternoon: Wolfgang Staehle Tuesday, March 6, 4:30 pm Jimmy Stewart Theater 185 Nassau Street Wolfgang Staehle was born in Stuttgart, Germany in 1950. He attended the Freie Kunstschule, in Stuttgart, and in 1976 he moved to New York to attend the School of Visual Arts, New York (BFA) where he studied closely with the Conceptual Artist Joseph Kosuth. After a successful career in various New York in European galleries in the 1980s, Staehle decided to work collectively, and in 1991 he founded The Thing, an innovative online forum for artists and cultural workers. The Thing began as a Bulletin Board System (BBS), a form of online community dialogue used before the advent of the World Wide Web. By the late 90s, The Thing grew into a diverse online community made up of dozens of members' Web sites, mailing lists, a successful Web hosting service, a community studio in Chelsea, and the first Web site devoted to Net Art, bbs.thing.net. In 1996, Staehle began to produce an ongoing series of live online video streams. The first of these works was Empire 24/7, a continuous recording of the top one-third of the Empire State Building that is broadcast live over the Internet. Staehle has followed Empire 24/7 with online streams of other buildings, landscapes and cityscapes such as Berlin's Fernsehturm, the Comburg Monastery in Germany, lower Manhattan before and after 9/11, and a Yanomami village in the Brazilian Amazon. He continues to expand this series while serving as the Executive Director of The Thing. URLs: postmedia.net newyorkmetro.com villagevoice.com For more information about the Program in Visual Arts: http://www.princeton.edu/~visarts/index.html For more information about the University Center for the Creative and Performing Arts: http://www.princeton.edu/arts/

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Colloquium Speaker Wed - 3/7/2007
by Ginny Hogan 05 Mar '07

05 Mar '07

Christina Leslie, Columbia University, will present her talk, "Learning Predictive Models of Gene Regulation". Talk will be held in COS 105 starting at 4:15pm.

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Multi-core processing lecture at 1:30 today
by Jaswinder Pal Singh 27 Feb '07

27 Feb '07

Prof Kunle Olukotun from Stanford is giving a guest lecture on multi-core processor architecture and software/models in COS 598A today, from 1:30 to 3 PM. Room coming shortly. This may be of interest to a broader audience given the strong multicore trend in processors going forward, and Prof. Olukotun is a leading researcher in the area. All are welcome to attend. Cheers, JP

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E Nabieva preFPO
by Melissa M Lawson 23 Feb '07

23 Feb '07

To correct my earlier announcement, Elena's preFPO is Tuesday (not Thursday) February 27. All other details remain the same. --Melissa

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E Nabieva preFPO
by Melissa M Lawson 22 Feb '07

22 Feb '07

Elena Nabieva will present her preFPO on Thursday February 27 at 11:15AM in Room 253, Carl Icahn Lab. The members of her committee are: Mona Singh, advisor; Tom Funkhouser, Olga Troyanskaya, readers; Bernard Chazelle, Ned Wingreen (MolBio), nonreaders. Everyone is invited to attend her talk. Her abstract follows below. ------------------------------ Abstract: Exploring the interplay between topology and function in protein interaction networks The emergence in recent years of numerous high-througphut experimental techniques in biology has lead to a new, genome-scale approach towards biological research. This high-throughput biology faces two complementary tasks: obtaining data on genomic scale and making sense of this data. It is the second task where computer scientists working in computational biology can make great contribution. One type of data obtained by high-throughput experiments is information about interactions among proteins, such as physical protein-protein interactions. This information can bring scientists closer to a solution to one of the most important problems in biology: understanding the role that different proteins play in the cell and the interplay among them. In my work, I look at the relationship between protein function and the protein's context in the interaction network from two angles: using interaction networks and information about other proteins to predict a protein's cellular role, and finding schemas, or recurring patterns of interaction among different types of proteins. In the first part of the talk, I explore the use of physical protein interaction networks for predicting the function of proteins. First, using as illustration some of the existing approaches to this problem, I discuss which topological properties of interaction networks should be taken into account by algorithms for predicting protein function based on physical interaction networks. Using these desiderata as guidelines, I introduce an original network-flow based algorithm called FunctionalFlow that exploits the underlying structure of protein interaction maps in order to predict protein function. In cross-validation testing on the yeast proteome, I show that FunctionalFlow has improved performance over previous methods in predicting the function of proteins with few (or no) annotated protein neighbors. I demonstrate that FunctionalFlow performs well because it takes advantage of both network topology and some measure of locality. Finally, I show that performance can be improved substantially as we consider multiple data sources and use them to create weighted interaction networks. In the second part of the talk, I take a different view at the topology-function relationship and use known information about protein molecular function and the physical interaction network to attempt to uncover organizational principles of the network. In this bottom-up view, I examine the networks from the perspective of ``pathway schemas,'' or recurring patterns of interaction among different types of proteins. Proteins in these schemas tend to act as functional units within diverse biological processes. I discuss computational methods for automatically uncovering statistically over-represented pathway schemas in protein-protein interaction maps, and touch upon the comparative-interactomics aspects of this problem. Coming back to the task of improving our understanding of protein function, I conclude by demonstrating how overrepresented schemas can be used to gain new insights about the biological function of proteins.

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Speaker Tomorrow
by Ginny Hogan 20 Feb '07

20 Feb '07

Unfortunatley, David Forsyth are colloquium speaker for tomorrow had to cancel his trip - there will be no colloquium talk - Ginny

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Colloquium Speaker 2/21/2007
by Ginny Hogan 19 Feb '07

19 Feb '07

David Forsyth, UIUC, will present his Talk, "Looking at People" Wed, Feb. 21st at 4:15pm COS 105 -

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